M. Klein

Ir.

20162019

Research output per year

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Research Output

  • 4 Article
  • 1 Dissertation (TU Delft)

Argonaute bypasses cellular obstacles without hindrance during target search

Cui, T., Klein, M., Hegge, J. W., Chandradoss, S. D., van der Oost, J., Depken, M. & Joo, C., 2019, In : Nature Communications. 10, 1, 11 p., 4390.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
  • 3 Citations (Scopus)
    30 Downloads (Pure)

    Right place, Right Time: Modeling the search time and specificity of Cas9 and Argonaute

    Klein, M., 2019, 191 p.

    Research output: ThesisDissertation (TU Delft)

    Open Access
    File
  • 25 Downloads (Pure)

    Hybridization Kinetics Explains CRISPR-Cas Off-Targeting Rules

    Klein, M., Eslami Mosallam, B., Gonzalez Arroyo, D. W. & Depken, M., 2018, In : Cell Reports. 22, 6, p. 1413-1423

    Research output: Contribution to journalArticleScientificpeer-review

    Open Access
    File
  • 31 Citations (Scopus)
    58 Downloads (Pure)

    Why Argonaute is needed to make microRNA target search fast and reliable

    Klein, M., Chandradoss, S. D., Depken, M. & Joo, C., 2017, In : Seminars in Cell and Developmental Biology. 65, p. 20-28

    Research output: Contribution to journalArticleScientificpeer-review

    Open Access
    File
  • 21 Citations (Scopus)
    37 Downloads (Pure)

    Cas3-Derived Target DNA Degradation Fragments Fuel Primed CRISPR Adaptation

    Künne, T., Kieper, S. N., Bannenberg, J. W., Vogel, A. I. M., Miellet, W. R., Klein, M., Depken, M., Suarez-Diez, M. & Brouns, S. J. J., 1 Sep 2016, In : Molecular Cell. 63, 5, p. 852-864 13 p.

    Research output: Contribution to journalArticleScientificpeer-review

    Open Access
    File
  • 61 Citations (Scopus)
    147 Downloads (Pure)