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Research Output

2020

A critical assessment of the Flory-Huggins (FH) theory to predict aqueous two-phase behaviour

Consorti Bussamra, B., Sietaram, D. L., Verheijen, P. J. T., Mussatto, S., Carvalho da Costa, A., van der Wielen, L. A. M. & Ottens, M., 2020, In : Separation and Purification Technology. 255, 117636.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
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1 Downloads (Pure)
2018

Experimental design for evaluating WWTP data by linear mass balances

Le, Q. H., Verheijen, P. J. T., van Loosdrecht, M. C. M. & Volcke, E. I. P., 1 Oct 2018, In : Water Research. 142, p. 415-425 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
File
8 Citations (Scopus)
7 Downloads (Pure)
2017

Brownian dynamics simulation of protein-polyelectrolyte particle formation and growth

Yu, M., Sediq, A. S., Every, H., Nejadnik, M. R., Verheijen, P., Jiskoot, W. & Witkamp, G-J., 2017.

Research output: Contribution to conferencePosterProfessional

Experience with large-scale dynamic model validation – application to industrial plant

Schmal, J. P. & Verheijen, P. J. T., 1 Oct 2017, Computer Aided Chemical Engineering. Elsevier, Vol. 40. p. 325-330 6 p. (Computer Aided Chemical Engineering; vol. 40).

Research output: Chapter in Book/Conference proceedings/Edited volumeChapterScientificpeer-review

Extreme calorie restriction in yeast retentostats induces uniform non-quiescent growth arrest

Bisschops, M., Luttik, M. (ed.), Doerr, A. (ed.), Verheijen, P. (ed.), Bruggeman, F. J. (ed.), Pronk, J. (ed.) & Daran-Lapujade, P. (ed.), 27 Sep 2017.

Research output: Contribution to conferencePosterScientific

2 Citations (Scopus)
2016

Extreme calorie restriction in yeast retentostats induces uniform non-quiescent growth arrest

Bisschops, M., Luttik, M., Doerr, A., Verheijen, P., Bruggeman, F. J., Pronk, J. & Daran-Lapujade, P., 2016.

Research output: Contribution to conferencePosterProfessional

Extreme calorie restriction in yeast retentostats induces uniform non-quiescent growth arrest

Bisschops, M., Luttik, M., Doerr, A., Verheijen, P., Bruggeman, F. J., Pronk, J. & Daran-Lapujade, P., 2016.

Research output: Contribution to conferencePosterProfessional

Open Access
File
13 Citations (Scopus)
36 Downloads (Pure)

Non-Linear Data Reconciliation for a Partial Nitritation (SHARON) Reactor

Le, Q. H., Verheijen, P. J. T., Mampaey, K. E., Loosdrecht, M. C. M. V. & Volcke, E. I. P., 2016, In : IFAC-PapersOnLine. 49, 7, p. 1139-1144 6 p.

Research output: Contribution to journalConference articleScientificpeer-review

1 Citation (Scopus)
2015

In vivo kinetic analysis of the penicillin biosynthesis pathway using PAA stimulus response experiments

Deshmukh, AT., Verheijen, PJT., Maleki Seifar, R. & Heijnen, JJ., 2015, In : Metabolic Engineering. 32, p. 155-173 19 p.

Research output: Contribution to journalArticleScientificpeer-review

8 Citations (Scopus)
2014

Mathematical model of adherent Vero cell growth and poliovirus production in animal component free medium

Ursache, RV., Thomassen, YE., van Eikenhorst, G., Verheijen, PJT. & Bakker, WAM., 2014, In : Bioprocess and Biosystems Engineering: bioreactors, upstream and downstream processes, measurement and control. 38, 3, p. 543-555

Research output: Contribution to journalArticleScientificpeer-review

Thermodynamic description of peptide adsorption on mixed-mode resins

Chilamkurthi, S., Mendez Sevillano, D., Albers, L. H. G., Sahoo, MR., Verheijen, PJT., van der Wielen, LAM., den Hollander, JL. & Ottens, M., 2014, In : Journal of Chromatography A. 1341, p. 41-49 9 p.

Research output: Contribution to journalArticleScientificpeer-review

5 Citations (Scopus)
2013

A kinetic modelling study of ethane cracking for optimal ethylene yield

van Goethem, MWM., Barendregt, S., Grievink, J., Verheijen, PJT., Dente, M. & Ranzi, E., 2013, In : Chemical Engineering Research & Design. 91, p. 1106-1110 5 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
22 Citations (Scopus)

A thermodynamic analysis of dicarboxylic acid production in microorganisms

Taymaz-Nikerel, H., Jamalzadeh, E., Espah Borujeni, A., Verheijen, PJT., van Gulik, WM. & Heijnen, JJ., 2013, Biothermodynamics: the role of thermodynamics in biochemical engineering. Lausanne, Switzerland: Urs von Stockar, p. 547-579 630 p.

Research output: Chapter in Book/Conference proceedings/Edited volumeChapterScientific

6 Citations (Scopus)

Efficient calculation of compound similarity based on maximum common subgraphs and its application to prediction of gene transcript levels

van Berlo, RJP., Winterbach, W., de Groot, MJL., Bender, A., Verheijen, PJT., Reinders, MJT. & de Ridder, D., 2013, In : International Journal of Bioinformatics Research and Applications. 9, p. 407-432 26 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
13 Citations (Scopus)

Integration of symbolic modelling within an equation based flowsheet package for steam pyrolysis

van Goethem, MWM. & Verheijen, PJT., 2013, In : Simulation Modelling Practice and Theory. 30, p. 74-89 16 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Microbial diversity differences within aerobic granular sludge and activated sludge flocs

Winkler, MKH., Kleerebezem, R., de Bruin, L., Verheijen, PJT., Abbas, BA. & Habermacher, JM., 2013, In : Applied Microbiology and Biotechnology. 97, 16, p. 7447-7458 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
72 Citations (Scopus)

Parameter identification of in vivo kinetic models: Limitations and challenges

Heijnen, JJ. & Verheijen, PJT., 2013, In : Biotechnology Journal. 8, p. 768-775 8 p.

Research output: Contribution to journalArticleScientificpeer-review

21 Citations (Scopus)
2012

A generalized reference state extends the applicability of approximative kinetics in metabolic engineering

Nikerel, IE., Verheijen, PJT. & Heijnen, JJ., 2012, In : Journal of Chemical Technology and Biotechnology. 87, 12, p. 1694-1701 8 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access

Model-based design of superior cell factory: an illustrative example of Penicillium chrysogenum

Nikerel, IE., Verheijen, PJT., van Gulik, WM. & Heijnen, JJ., 2012, Systems Metabolic Engineering. C, W. & S.Y., L. (eds.). Dordrecht, Netherlands: Springer, p. 221-270 387 p.

Research output: Chapter in Book/Conference proceedings/Edited volumeChapterScientific

Open Access
2 Citations (Scopus)

pH-Dependent uptake of fumaric acid in Saccharomyces cerevisiae under anaerobic conditions

Jamalzadeh, E., Verheijen, PJT., Heijnen, JJ. & van Gulik, WM., 2012, In : Applied and Environmental Microbiology. 78, 3, p. 705-716 12 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
17 Citations (Scopus)

Understanding in vivo kinetics and transport through stimulus response experiments: Penicillium chrysogenum as host strain

Deshmukh, AT., Verheijen, PJT., Maleki Seifar, R., Heijnen, JJ. & van Gulik, WM., 2012.

Research output: Contribution to conferencePosterProfessional

Unraveling in vivo kinetics of penicillin biosyntheses pathway

Deshmukh, AT., Verheijen, PJT., Maleki Seifar, R., Heijnen, JJ. & van Gulik, WM., 2012.

Research output: Contribution to conferencePosterProfessional

Use of sequential batch fermentations to characterize the impact of mild hypothermic temperatures on the anaerobic stoichiometry and kinetics of Saccharomyces cerevisiae

da Cruz, ALB., Verbon, AJ., Geurink, LJ., Verheijen, PJT., Heijnen, JJ. & van Gulik, WM., 2012, In : Biotechnology and Bioengineering. 109, 7, p. 1735-1744 10 p.

Research output: Contribution to journalArticleScientificpeer-review

10 Citations (Scopus)
2011
Open Access
9 Citations (Scopus)

Cytosolic NADPH balancing in Penicillium chrysogenum cultivated on mixtures of glucose and ethanol

Zhao, Z., Kuijvenhoven, K., van Gulik, WM., Heijnen, JJ., van Winden, WA. & Verheijen, PJT., 2011, In : Applied Microbiology and Biotechnology. 89, p. 63-72 10 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
7 Citations (Scopus)

How to obtain true and accurate rate values

Heijnen, JJ. & Verheijen, PJT., 2011, Methods in enzymology. Jameson, D. & Verma, M. (eds.). Burlington: Elsevier, p. 457-508 715 p.

Research output: Chapter in Book/Conference proceedings/Edited volumeChapterScientific

1 Citation (Scopus)

Model-based rational strategy for chromatographic resin selection

Nfor, BK., Zuluaga, DS., Verheijen, PJT., Verhaert, PDE., van der Wielen, LAM. & Ottens, M., 2011, In : Biotechnology Progress. 27, 6

Research output: Contribution to journalArticleScientificpeer-review

29 Citations (Scopus)
2010

Dynamic gene expression regulation model for growth and penicillin production in Penicillium chrysogenum

Douma, RD., Verheijen, PJT., de Laat, WTAM., Heijnen, JJ. & van Gulik, WM., 2010.

Research output: Contribution to conferencePosterProfessional

33 Citations (Scopus)

Dynamic gene expression regulation model for growth and penicillin production in Penicillium chrysogenum

Douma, RD., Verheijen, PJT., de Laat, WTAM., Heijnen, JJ. & van Gulik, WM., 2010, In : Biotechnology and Bioengineering. 106, 4, p. 608-618 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
33 Citations (Scopus)

Genome-derived minimal metabolic models for Escherichia coli MG1655 with estimated in-vivo resporatory ATP stoichiometry

Taymaz-Nikerel, H., Espah Borujeni, A., Verheijen, PJT., Heijnen, JJ. & van Gulik, WM., 2010, In : Biotechnology and Bioengineering. 107, 2, p. 369-381 13 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
50 Citations (Scopus)

Isotopic transient data for identification of intracellular fluxes in Penicillium chrysogenum

Zhao, Z., ten Pierick, A., Ras, C., Verheijen, PJT., Heijnen, JJ., van Gulik, WM. & Wahl, SA., 2010.

Research output: Contribution to conferencePosterProfessional

Isotopic transient data for identification of intracellular fluxes in Penicillium chrysogenum

Zhao, Z., ten Pierick, A., Ras, C., Verheijen, PJT., Heijnen, JJ., van Gulik, WM. & Wahl, SA., 2010.

Research output: Contribution to conferencePosterProfessional

Isotopic transients under metabolic steady state in Penicillium chrysogenum

Zhao, Z., ten Pierick, A., Ras, C., Verheijen, PJT., Heijnen, JJ., van Gulik, WM. & Wahl, SA., 2010.

Research output: Contribution to conferencePosterProfessional

Model-based, thermo-physical optimisation for high olefin yield in steam cracking reactors

van Goethem, MWM., Barendregt, S., Grievink, J., Moulijn, JA. & Verheijen, PJT., 2010, In : Chemical Engineering Research & Design. 88, 10, p. 1305-1319 15 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
15 Citations (Scopus)

Time-scala based metabolic network reduction and application in the 13C flux analysis of Penicillium chrysogenum

Zhao, Z., Perlasca, M., Verheijen, PJT., Wahl, SA., Heijnen, JJ. & van Gulik, WM., 2010.

Research output: Contribution to conferencePosterProfessional

Time-scale based metabolic network reduction for 13C flux analysis

Zhao, Z., Wahl, SA., Verheijen, PJT., Heijnen, JJ. & van Gulik, WM., 2010.

Research output: Contribution to conferencePosterProfessional

Time-scale based metabolic network reduction for 13C flux analysis

Zhao, Z., Wahl, SA., Verheijen, PJT., Heijnen, JJ. & van Gulik, WM., 2010.

Research output: Contribution to conferencePosterProfessional

2009

Construction of kinetic models for metabolic reaction networks: Lessons learned in analyzing short term stimulus response data

Nikerel, IE., Canelas, A., Jol, SJ., Verheijen, PJT. & Heijnen, JJ., 2009, MATHMOD 09 Vienna. Torch, I. & Breitenecker, F. (eds.). Vienna: Argesim, p. 805-814 10 p.

Research output: Chapter in Book/Conference proceedings/Edited volumeConference contributionScientific

Data reconciliation and error detection

Verheijen, PJT., 2009, The metabolic pathway engineering handbook: Fundamentals. van Gulik, WM. (ed.). Boca Raton, Florida, USA: CRC Press, p. 8-1-8-13 678 p.

Research output: Chapter in Book/Conference proceedings/Edited volumeChapterScientific

5 Citations (Scopus)

Hybrid system modeling and identification of cell biology systems:perspectives and challenges

Vries, D., Verheijen, PJT. & den Dekker, AJ., 2009, Proceedings of the 15th symposium on system identification SYSID 2009. Basseville, M. (ed.). Saint-Malo, France: SYSID, p. 227-232 6 p.

Research output: Chapter in Book/Conference proceedings/Edited volumeConference contributionScientificpeer-review

5 Citations (Scopus)

Identification of lin-log kinetics for the central metabolism of E. coli

Bernaerts, K., Taymaz, H., Heijnen, JJ., van Gulik, WM. & Verheijen, PJT., 2009, Proceeding of the Third International Conference on Foundations of System Biology in Engineering. Hahn, J. & Rao, C. (eds.). Denver, Colorado: FOSBE, p. 189-192 4 p.

Research output: Chapter in Book/Conference proceedings/Edited volumeConference contributionScientific

Identification of lin-log kinetics for the central metabolism of E. coli

Bernaerts, K., Taymaz, H., Heijnen, JJ., van Gulik, WM. & Verheijen, PJT., 2009.

Research output: Contribution to conferencePosterProfessional

Metabolic engineering and metabolic modelling of Escherichia coli for the production of chemicals from renewable resources (Memore)

de Mey, M., Beauprez, J., Bhagwat, A., Boogmans, S., Donckels, BMR., Foulquie-Moreno, M., Lequeux, G., Maertens, J., Taymaz, H., Van Horen, E., Waegeman, H., Cunin, R., Charlier, D., Vanrolleghem, P., De Baets, B., van Dam, JC., van Gulik, WM., Verheijen, PJT., Heijnen, JJ., Vandamme, E. & 1 others, Soetaert, W., 2009.

Research output: Contribution to conferenceAbstractScientific

Metabolite and reaction inference based on enzyme specificities

de Groot, MJL., van Berlo, RJP., van Winden, WA., Verheijen, PJT., Reinders, MJT. & de Ridder, D., 2009, In : Bioinformatics. 25, 22, p. 2975-2982 8 p.

Research output: Contribution to journalArticleScientificpeer-review

13 Citations (Scopus)
12 Citations (Scopus)

Model reduction and a priori kinetic parameter identifiability analysis using metabolome time series for metabolic reaction networks with linlog kinetics

Nikerel, IE., van Winden, WA., Verheijen, PJT. & Heijnen, JJ., 2009, In : Metabolic Engineering. 11, p. 20-30 11 p.

Research output: Contribution to journalArticleScientificpeer-review

Open Access
55 Citations (Scopus)

Optimal input design for PWA biological cell systems

Vries, D., Verheijen, PJT. & den Dekker, AJ., 2009.

Research output: Contribution to conferencePosterProfessional

2008

Identifying the regulatory structure of metabolic networks: a constrained optimization approach

Bellomo, D., de Ridder, D., Rossell, S., Verheijen, PJT., Reinders, MJT. & Heijnen, JJ., 2008, Proceedings of the fourteenth annual conference of the Advanced School for Computing and Imaging. Smit, GJM., Epema, DHJ. & Lew, MS. (eds.). Delft: ASCI, p. 250-257 8 p.

Research output: Chapter in Book/Conference proceedings/Edited volumeConference contributionScientificpeer-review