3D ultrasound imaging: Fast and cost-effective morphometry of musculoskeletal tissue

Guido Weide, Stephan Van Der Zwaard, Peter A.J.B.M. Huijing, Richard T. Jaspers*, Jaap Harlaar

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

24 Citations (Scopus)


The developmental goal of 3D ultrasound imaging (3DUS) is to engineer a modality to perform 3D morphological ultrasound analysis of human muscles. 3DUS images are constructed from calibrated freehand 2D B-mode ultrasound images, which are positioned into a voxel array. Ultrasound (US) imaging allows quantification of muscle size, fascicle length, and angle of pennation. These morphological variables are important determinants of muscle force and length range of force exertion. The presented protocol describes an approach to determine volume and fascicle length of m. vastus lateralis and m. gastrocnemius medialis. 3DUS facilitates standardization using 3D anatomical references. This approach provides a fast and cost-effective approach for quantifying 3D morphology in skeletal muscles. In healthcare and sports, information on the morphometry of muscles is very valuable in diagnostics and/or follow-up evaluations after treatment or training.

Original languageEnglish
Article numbere55943
JournalJournal of Visualized Experiments
Issue number129
Publication statusPublished - 2017
Externally publishedYes

Bibliographical note

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  • 3D ultrasound
  • Architecture
  • Fascicle length
  • Issue 129
  • M. gastrocnemius medialis
  • M. quadriceps femoris
  • M. vastus lateralis
  • Medicine
  • Morphology
  • Muscle geometry
  • Muscle volume
  • Skeletal muscle


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