A 0.5 μA/Channel front-end for implantable and external ambulatory ECG recorders

Yasser Rezaeiyan, Milad Zamani, Omid Shoaei, Wouter A. Serdijn

Research output: Contribution to journalArticleScientificpeer-review

2 Citations (Scopus)
5 Downloads (Pure)


There is an increasing demand for low power, low voltage, and small size analog readout bio-potential systems. This paper presents an analog front-end for measuring the intra-cardiac signals in implantable and also external ambulatory ECG cardiac recording applications. The analog front-end benefits from voltage to frequency conversion without conventional analog to digital conversion and thereby achieves a very low power consumption. The frequency averaging digital reconstruction makes an intrinsic low pass filter of which the cut-off frequency changes with the averaging interval and eliminates the need for an analog filter in this system. Furthermore, this feature enables the development of a general purpose analog readout bio-potential measurement system with programmable bandwidth. The proposed IC is fabricated in a 0.18 μm CMOS process and occupies 0.396 mm2. It can measure intra-cardiac bio-potentials with 9.2-bit resolution while consuming just 0.5 μA per channel from a 1 V supply. The input referred noise of the intra-cardiac signal readout channel is 2 μVrms.

Original languageEnglish
Pages (from-to)79-85
Number of pages7
JournalMicroelectronics Journal
Publication statusPublished - 2018


  • Analog integrated circuits
  • Bio-potential amplifier
  • ECG
  • IECG
  • Instrumentation amplifier
  • Low power
  • Programmable gain amp

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