A Biocatalytic Aza-Achmatowicz Reaction

Elena Fernández-Fueyo, Sabry H H Younes, Stefan Van Rootselaar, René W M Aben, Rokus Renirie, Ron Wever, Dirk Holtmann, Floris P J T Rutjes, Frank Hollmann

Research output: Contribution to journalArticleScientificpeer-review

26 Citations (Scopus)
21 Downloads (Pure)


A catalytic, enzyme-initiated (aza-) Achmatowicz reaction is presented. The involvement of a robust vanadium-dependent peroxidase from Curvularia inaequalis allows the simple use of H2O2 and catalytic amounts of bromide.

Original languageEnglish
Pages (from-to)5904-5907
Number of pages4
JournalACS Catalysis
Issue number9
Publication statusPublished - 2016


  • Achmatowicz reaction
  • biocatalysis
  • hypohalogenites
  • oxidation
  • peroxidase

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