TY - JOUR
T1 - Adsorption of molybdenum on Zr-based MOFs for potential application in the 99Mo/99mTc generator
AU - Ma, Chao
AU - Vasileiadis, Alexandros
AU - Wolterbeek, Hubert T.
AU - Denkova, Antonia G.
AU - Serra Crespo, Pablo
PY - 2021
Y1 - 2021
N2 - The potential of the metal–organic framework UiO-66 and its functionalized derivatives for their utilization in the 99Mo/99mTc generator was assessed. Molybdenum adsorption experiments, structure characterization, molecular simulations and column experiments with molybdenum-99 were carried out. The results showed that the maximum molybdenum adsorption capacity achieved for UiO-66 was 335 mg g−1. Adsorption on the surface of the UiO-66 occurs via electrostatic interaction and DFT calculations verified the enhanced affinity between the adsorbents and the molybdenum ions by Zr-O-Mo coordination, anion-π as well as hydrogen bonds. In addition, the performance of a 99Mo/99mTc generator fabricated with Form-UiO-66 was evaluated. The results showed that adsorption was comparable with the experiments using non-active molybdenum and that the 99mTc elution efficiency of around 70% could be achieved without zirconium breakthrough.
AB - The potential of the metal–organic framework UiO-66 and its functionalized derivatives for their utilization in the 99Mo/99mTc generator was assessed. Molybdenum adsorption experiments, structure characterization, molecular simulations and column experiments with molybdenum-99 were carried out. The results showed that the maximum molybdenum adsorption capacity achieved for UiO-66 was 335 mg g−1. Adsorption on the surface of the UiO-66 occurs via electrostatic interaction and DFT calculations verified the enhanced affinity between the adsorbents and the molybdenum ions by Zr-O-Mo coordination, anion-π as well as hydrogen bonds. In addition, the performance of a 99Mo/99mTc generator fabricated with Form-UiO-66 was evaluated. The results showed that adsorption was comparable with the experiments using non-active molybdenum and that the 99mTc elution efficiency of around 70% could be achieved without zirconium breakthrough.
KW - Mo/Tc generator
KW - Density functional theory
KW - Interaction mechanism
KW - Molybdenum adsorption
KW - UiO-66
UR - http://www.scopus.com/inward/record.url?scp=85116721025&partnerID=8YFLogxK
U2 - 10.1016/j.apsusc.2021.151340
DO - 10.1016/j.apsusc.2021.151340
M3 - Article
AN - SCOPUS:85116721025
VL - 572
JO - Applied Surface Science
JF - Applied Surface Science
SN - 0169-4332
M1 - 151340
ER -