TY - JOUR
T1 - Alternative coenzymes for biocatalysis
AU - Guarneri, Alice
AU - van Berkel, Willem JH
AU - Paul, Caroline E.
N1 - Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.
PY - 2019
Y1 - 2019
N2 - Coenzymes are ubiquitous in Nature, assisting in enzyme-catalysed reactions. Several coenzymes, nicotinamides and flavins, have been known for close to a century, whereas variations of those organic molecules have more recently come to light. In general, the requirement of these coenzymes imposes certain constraints for in vitro enzyme use in biocatalytic processes. Alternative coenzymes have risen to circumvent the cost factor, tune reaction rates or obtain different chemical reactivity. This review will focus on these alternatives and their role and applications in biocatalysis.
AB - Coenzymes are ubiquitous in Nature, assisting in enzyme-catalysed reactions. Several coenzymes, nicotinamides and flavins, have been known for close to a century, whereas variations of those organic molecules have more recently come to light. In general, the requirement of these coenzymes imposes certain constraints for in vitro enzyme use in biocatalytic processes. Alternative coenzymes have risen to circumvent the cost factor, tune reaction rates or obtain different chemical reactivity. This review will focus on these alternatives and their role and applications in biocatalysis.
UR - http://www.scopus.com/inward/record.url?scp=85060853531&partnerID=8YFLogxK
U2 - 10.1016/j.copbio.2019.01.001
DO - 10.1016/j.copbio.2019.01.001
M3 - Review article
AN - SCOPUS:85060853531
SN - 0958-1669
VL - 60
SP - 63
EP - 71
JO - Current Opinion in Biotechnology
JF - Current Opinion in Biotechnology
ER -