Analysis of Motility in Apparently Normal Small Bowel–Relationship to Crohn’s Symptoms

R Gollifer, A Menys, J Makanyanga, C Puylaert, Frans Vos, Jaap Stoker, D Atkinson, Stuart A. Taylor

    Research output: Chapter in Book/Conference proceedings/Edited volumeConference contributionScientificpeer-review

    Abstract

    Crohn’s disease (CD) patients often suffer abdominal symptoms even when their disease is apparently in remission with no identifiable active inflammation.1 Ongoing aberrant gut motility has been postulated as a cause, and this can now be quantified using MRI.2 This study tested the association between abdominal symptoms based on the Harvey-Bradshaw Index (HBI) and MRI derived motility metrics in morphologically healthy small bowel in CD patients. An inverse association was found between reduced motility spatial variation across the small bowel and symptoms, particularly diarrhoea. This association was strongest when HBI scores were higher.
    Original languageEnglish
    Title of host publicationProceedings of the ISMRM Annual Meeting & Exhibition 2017
    PublisherISMRM
    Pages4967-4967
    Publication statusPublished - 7 Apr 2017
    EventISMRM (International Society for Magnetic Resonance in Medicine) Annual Meeting & Exhibition - Honolulu, United States
    Duration: 22 Apr 201727 Apr 2017
    Conference number: 25

    Conference

    ConferenceISMRM (International Society for Magnetic Resonance in Medicine) Annual Meeting & Exhibition
    CountryUnited States
    CityHonolulu
    Period22/04/1727/04/17

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