Atomic scale surface engineering of micro- to nano-sized pharmaceutical particles for drug delivery applications

D. Zhang; M. J. Quayle; G. Petersson; J. R. Van Ommen; S. Folestad

doi:10.1039/c7nr03261g

Atomic scale surface engineering of micro- to nano-sized pharmaceutical particles for drug delivery applications

D. Zhang, M. J. Quayle, G. Petersson, J. R. Van Ommen, S. Folestad^*

^*Corresponding author for this work

ChemE/Product and Process Engineering

Research output: Contribution to journal › Article › Scientific › peer-review

24 Citations (Scopus)

Abstract

Atomic layer deposition on pharmaceutical particles for drug delivery applications is demonstrated using assisted fluidized bed dry powder processing. Complete and conformal layering is achieved on particle sizes from the lower micron to upper nanometer range under near ambient conditions. As few as 2-14 atomic alumina layers alter particle properties: dissolution, dispersibility and heat transfer.

Original language	English
Pages (from-to)	11410-11417
Number of pages	8
Journal	Nanoscale
Volume	9
Issue number	32
DOIs	https://doi.org/10.1039/c7nr03261g
Publication status	Published - 28 Aug 2017

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title = "Atomic scale surface engineering of micro- to nano-sized pharmaceutical particles for drug delivery applications",

abstract = "Atomic layer deposition on pharmaceutical particles for drug delivery applications is demonstrated using assisted fluidized bed dry powder processing. Complete and conformal layering is achieved on particle sizes from the lower micron to upper nanometer range under near ambient conditions. As few as 2-14 atomic alumina layers alter particle properties: dissolution, dispersibility and heat transfer.",

author = "D. Zhang and Quayle, {M. J.} and G. Petersson and {Van Ommen}, {J. R.} and S. Folestad",

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AU - Zhang, D.

AU - Quayle, M. J.

AU - Petersson, G.

AU - Van Ommen, J. R.

AU - Folestad, S.

PY - 2017/8/28

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AB - Atomic layer deposition on pharmaceutical particles for drug delivery applications is demonstrated using assisted fluidized bed dry powder processing. Complete and conformal layering is achieved on particle sizes from the lower micron to upper nanometer range under near ambient conditions. As few as 2-14 atomic alumina layers alter particle properties: dissolution, dispersibility and heat transfer.

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U2 - 10.1039/c7nr03261g

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M3 - Article

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SP - 11410

EP - 11417

JO - Nanoscale

JF - Nanoscale

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ER -

Atomic scale surface engineering of micro- to nano-sized pharmaceutical particles for drug delivery applications

Abstract

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