Building a community to engineer synthetic cells and organelles from the bottom-up

Oskar Staufer; Jacqueline A. DE LORA; Eleonora Bailoni; Alisina Bazrafshan; Amelie S. Benk; Kevin Jahnke; Zachary A. Manzer; Marileen Dogterom; Gabriel P. López; null More Authors

doi:10.7554/eLife.73556

Building a community to engineer synthetic cells and organelles from the bottom-up

Oskar Staufer^*, Jacqueline A. DE LORA, Eleonora Bailoni, Alisina Bazrafshan, Amelie S. Benk, Kevin Jahnke, Zachary A. Manzer, Marileen Dogterom, Gabriel P. López, More Authors

^*Corresponding author for this work

BN/Marileen Dogterom Lab

Research output: Contribution to journal › Article › Scientific › peer-review

22 Citations (Scopus)

30 Downloads (Pure)

Abstract

Employing concepts from physics, chemistry and bioengineering, 'learning-by-building' approaches are becoming increasingly popular in the life sciences, especially with researchers who are attempting to engineer cellular life from scratch. The SynCell2020/21 conference brought together researchers from different disciplines to highlight progress in this field, including areas where synthetic cells are having socioeconomic and technological impact. Conference participants also identified the challenges involved in designing, manipulating and creating synthetic cells with hierarchical organization and function. A key conclusion is the need to build an international and interdisciplinary research community through enhanced communication, resource-sharing, and educational initiatives.

Original language	English
Article number	e73556
Number of pages	10
Journal	eLife
Volume	10
DOIs	https://doi.org/10.7554/eLife.73556
Publication status	Published - 2021

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elife-73556-v2Final published version, 601 KBLicence: CC BY

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AU - Staufer, Oskar

AU - DE LORA, Jacqueline A.

AU - Bailoni, Eleonora

AU - Bazrafshan, Alisina

AU - Benk, Amelie S.

AU - Jahnke, Kevin

AU - Manzer, Zachary A.

AU - Dogterom, Marileen

AU - López, Gabriel P.

AU - More Authors, null

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AB - Employing concepts from physics, chemistry and bioengineering, 'learning-by-building' approaches are becoming increasingly popular in the life sciences, especially with researchers who are attempting to engineer cellular life from scratch. The SynCell2020/21 conference brought together researchers from different disciplines to highlight progress in this field, including areas where synthetic cells are having socioeconomic and technological impact. Conference participants also identified the challenges involved in designing, manipulating and creating synthetic cells with hierarchical organization and function. A key conclusion is the need to build an international and interdisciplinary research community through enhanced communication, resource-sharing, and educational initiatives.

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Building a community to engineer synthetic cells and organelles from the bottom-up

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