Cardiac Shear Wave Velocity Detection in the Porcine Heart

Hendrik J. Vos, Bas M. van Dalen, Ilkka Heinonen, Johan G. Bosch, Oana Sorop, Dirk J. Duncker, Antonius F.W. van der Steen, Nico de Jong

    Research output: Contribution to journalArticleScientificpeer-review

    32 Citations (Scopus)
    43 Downloads (Pure)

    Abstract

    Cardiac muscle stiffness can potentially be estimated non-invasively with shear wave elastography. Shear waves are present on the septal wall after mitral and aortic valve closure, thus providing an opportunity to assess stiffness in early systole and early diastole. We report on the shear wave recordings of 22 minipigs with high-frame-rate echocardiography. The waves were captured with 4000 frames/s using a programmable commercial ultrasound machine. The wave pattern was extracted from the data through a local tissue velocity estimator based on one-lag autocorrelation. The wave propagation velocity was determined with a normalized Radon transform, resulting in median wave propagation velocities of 2.2 m/s after mitral valve closure and 4.2 m/s after aortic valve closure. Overall the velocities ranged between 0.8 and 6.3 m/s in a 95% confidence interval. By dispersion analysis we found that the propagation velocity only mildly increased with shear wave frequency.

    Original languageEnglish
    Pages (from-to)753-764
    Number of pages12
    JournalUltrasound in Medicine & Biology
    Volume43
    Issue number4
    DOIs
    Publication statusPublished - 1 Apr 2017

    Keywords

    • Echocardiography
    • High-frame-rate imaging
    • Shear wave elastography
    • Stiffness measurements
    • Valve closure

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