Catalytic control in out-of-equilibrium assembly systems

Susan van Rossum

Research output: ThesisDissertation (TU Delft)

77 Downloads (Pure)


Nature is capable of constantly adapting some of its assembled structures in response to external and internal signals. For instance, microtubuli grow and shrink upon cell division and cellular transport. Furthermore, actin fibers play a major role in muscle contraction and cell signaling. To achieve these transient functions, such assembled structures operate in an out-of-equilibrium state. Energy input and dissipation enables structure growth and subsequent collapse. Regulating the energy input with fuel concentration and the activity of associated enzymatically catalyzed processes leads to a high level of kinetic control in biological out-of-equilibrium processes....
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Delft University of Technology
  • Eelkema, R., Supervisor
  • van Esch, J.H., Supervisor
Award date29 Oct 2019
Print ISBNs978-94-028-1708-9
Publication statusPublished - 2019

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