Characterisation of the HollandPTC R&D proton beamline for physics and radiobiology studies

M. Rovituso*, C. F. Groenendijk, E.M. van der Wal, A. Ibrahimi, H. Rituerto Prieto, J. M.C. Brown, U. Weber, D. Lathouwers, M. van Vulpen, More Authors

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

Abstract

HollandPTC is an independent outpatient center for proton therapy, scientific research, and education. Patients with different types of cancer are treated with Intensity Modulated Proton Therapy (IMPT). Additionally, the HollandPTC R&D consortium conducts scientific research into the added value and improvements of proton therapy. To this end, HollandPTC created clinical and pre-clinical research facilities including a versatile R&D proton beamline for various types of biologically and technologically oriented research. In this work, we present the characterization of the R&D proton beamline of HollandPTC. Its pencil beam mimics the one used for clinical IMPT, with energy ranging from 70 up to 240 MeV, which has been characterized in terms of shape, size, and intensity. For experiments that need a uniform field in depth and lateral directions, a dual ring passive scattering system has been designed, built, and characterized. With this system, field sizes between 2 × 2 cm2 and 20 × 20 cm2 with 98 % uniformity are produced with dose rates ranging from 0.5 Gy/min up to 9 Gy/min. The unique and customized support of the dual ring system allows switching between a pencil beam and a large field in a very simple and fast way, making the HollandPTC R&D proton beam able to support a wide range of different applications.

Original languageEnglish
Article number104883
Number of pages10
JournalPhysica Medica
Volume130
DOIs
Publication statusPublished - 2025

Bibliographical note

Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care
Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.

Keywords

  • Experimental characterization
  • Proton beam line
  • Proton radiobiology
  • R&D

Fingerprint

Dive into the research topics of 'Characterisation of the HollandPTC R&D proton beamline for physics and radiobiology studies'. Together they form a unique fingerprint.

Cite this