Chemoenzymatic Halocyclization of γ,δ-Unsaturated Carboxylic Acids and Alcohols

Sabry H.H. Younes, Florian Tieves, Dongming Lan, Yonghua Wang, Philipp Süss, Henrike Brundiek, Ron Wever, Frank Hollmann

Research output: Contribution to journalArticleScientificpeer-review

8 Citations (Scopus)
59 Downloads (Pure)


A chemoenzymatic method for the halocyclization of unsaturated alcohols and acids by using the robust V-dependent chloroperoxidase from Curvularia inaequalis (CiVCPO) as catalyst has been developed for the in situ generation of hypohalites. A broad range of halolactones and cyclic haloethers are formed with excellent performance of the biocatalyst.

Original languageEnglish
Pages (from-to)97-101
Number of pages6
Issue number1
Publication statusPublished - 2019


  • biocatalysis
  • enzymes
  • etherification
  • haloperoxidases
  • lactones

Fingerprint Dive into the research topics of 'Chemoenzymatic Halocyclization of γ,δ-Unsaturated Carboxylic Acids and Alcohols'. Together they form a unique fingerprint.

Cite this