Chiral amine synthesis by oxidoreductases

Research output: ThesisDissertation (TU Delft)

Abstract

Chiral amines are valuable compounds in the pharmaceutical industry. These valuable compounds have been made via organocatalysis, metallocatalysis but in the last two decades also via biocatalysis. Enzymes are highly selective, making them attractive catalysts to target chiral amine synthesis. The aim of this dissertation was to apply different biocatalytic pathways with oxidoreductases to synthesize chiral amines.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Delft University of Technology
Supervisors/Advisors
  • Paul, C.E., Supervisor
  • Hanefeld, U., Supervisor
Award date3 Feb 2025
Print ISBNs978-94-6384-715-5
DOIs
Publication statusPublished - 2024

Keywords

  • chiral amines
  • reductive amination
  • oxidoreductase

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