Comparing the topology of phylogenetic network generators

Remie Janssen, Pengyu Liu*

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

1 Citation (Scopus)
2 Downloads (Pure)


Phylogenetic networks represent evolutionary history of species and can record natural reticulate evolutionary processes such as horizontal gene transfer and gene recombination. This makes phylogenetic networks a more comprehensive representation of evolutionary history compared to phylogenetic trees. Stochastic processes for generating random trees or networks are important tools in evolutionary analysis, especially in phylogeny reconstruction where they can be utilized for validation or serve as priors for Bayesian methods. However, as more network generators are developed, there is a lack of discussion or comparison for different generators. To bridge this gap, we compare a set of phylogenetic network generators by profiling topological summary statistics of the generated networks over the number of reticulations and comparing the topological profiles.

Original languageEnglish
Article number2140012
Number of pages33
JournalJournal of Bioinformatics and Computational Biology
Issue number6
Publication statusPublished - 2021


  • network generator
  • network topology
  • Phylogenetic network


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