CRISPR-Cas Systems Reduced to a Minimum

Cristóbal Almendros, Sebastian N. Kieper, Stan J.J. Brouns*

*Corresponding author for this work

Research output: Contribution to journalReview articleScientificpeer-review


In two recent studies in Molecular Cell, Wright et al. (2019) report complete spacer integration by a Cas1 mini-integrase and Edraki et al. (2019) describe accurate genome editing by a small Cas9 ortholog with less stringent PAM requirements.

Original languageEnglish
Pages (from-to)641-642
JournalMolecular Cell
Issue number4
Publication statusPublished - 21 Feb 2019


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