Realistic microscopic traffic simulation is essential for prospective evaluation of the potential impacts of new traffic control strategies. Freeway corridors with interacting bottlenecks and dedicated lanes generate complex traffic flow phenomena and congestion patterns, which are difficult to reproduce with existing microscopic simulation models. This paper discusses two alternative driving behavior models that are capable of modeling freeways with multiple bottlenecks and dedicated lanes over an extended period with varying demand levels. The models have been calibrated using archived data from a complicated 13-mile long section of the northbound SR99 freeway near Sacramento, California, for an 8-hour time period in which the traffic fluctuated from free-flow to congested conditions. The corridor includes multiple bottlenecks, multiple entry and exit ramps, and an HOV lane. Calibration results show extremely good agreement between field data and model predictions. The models have been cross-validated and produced similar macroscopic traffic performance. The main behavior that should be captured for successful modeling of such a complex corridor includes the anticipative and cooperative driver behavior near merges, lane preference in presence of dedicated lanes, and variations in desired headway along the corridor.