Cryogenic transmission electron microscopy: the technique of choice for the characterization of polymeric nanocarriers

Adrianus C. Laan; Antonia G. Denkova

doi:10.1186/s13550-017-0290-3

Cryogenic transmission electron microscopy: the technique of choice for the characterization of polymeric nanocarriers

Adrianus C. Laan^*, Antonia G. Denkova

^*Corresponding author for this work

RST/Applied Radiation & Isotopes

Research output: Contribution to journal › Letter › Scientific › peer-review

9 Citations (Scopus)

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Abstract

This letter is meant to make scientists aware of the proper application of transmission electron microscopy (TEM) for the assessment of polymeric self-assemblies. Cryogenic (cryo)-TEM should be the method of choice. Here, we show the difference in morphologies observed in the same sample when using cryo-TEM and when using TEM with drying, demonstrating the importance of choosing the proper method.

Original language	English
Article number	44
Number of pages	2
Journal	EJNMMI Research
Volume	7
Issue number	1
DOIs	https://doi.org/10.1186/s13550-017-0290-3
Publication status	Published - 2017

Keywords

OA-Fund TU Delft

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10.1186/s13550-017-0290-3

s13550-017-0290-3Final published version, 499 KBLicence: CC BY

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abstract = "This letter is meant to make scientists aware of the proper application of transmission electron microscopy (TEM) for the assessment of polymeric self-assemblies. Cryogenic (cryo)-TEM should be the method of choice. Here, we show the difference in morphologies observed in the same sample when using cryo-TEM and when using TEM with drying, demonstrating the importance of choosing the proper method.",

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AB - This letter is meant to make scientists aware of the proper application of transmission electron microscopy (TEM) for the assessment of polymeric self-assemblies. Cryogenic (cryo)-TEM should be the method of choice. Here, we show the difference in morphologies observed in the same sample when using cryo-TEM and when using TEM with drying, demonstrating the importance of choosing the proper method.

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Cryogenic transmission electron microscopy: the technique of choice for the characterization of polymeric nanocarriers

Abstract

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