Deep confocal fluorescence microscopy with single-photon superconducting nanowire detector

Fei Xia*, Monique Gevers, Andreas Fognini, Aaron T. Mok, Bo Li, Najva Akabri, Iman Esmaeil Zadeh, Jessie Qin-Dregely, Chris Xu

*Corresponding author for this work

Research output: Chapter in Book/Conference proceedings/Edited volumeConference contributionScientificpeer-review

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Abstract

Using short-wave infrared wavelength advantages, we demonstrate one-photon fluorescence confocal microscopy of adult mouse brains with penetration depths up to 1.7mm. This is achieved by labeling quantum dots with 1300 nm excitation and 1700 nm emission and detecting them with a single-photon superconducting nanowire detector.

Original languageEnglish
Title of host publicationAdvanced Photon Counting Techniques XVI
EditorsMark A. Itzler, Joshua C. Bienfang, K. Alex McIntosh
PublisherSPIE
Number of pages6
ISBN (Electronic)9781510650541
DOIs
Publication statusPublished - 2022
EventAdvanced Photon Counting Techniques XVI 2022 - Virtual, Online
Duration: 6 Jun 202212 Jun 2022

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume12089
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

ConferenceAdvanced Photon Counting Techniques XVI 2022
CityVirtual, Online
Period6/06/2212/06/22

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