Depth resolved quantitative profiling of stratum corneum lipids and water content using short-wave infrared spectroscopy

Anna Ezerskaia, Silvania F. Pereira, H. Paul Urbach, Babu Varghese

Research output: Chapter in Book/Conference proceedings/Edited volumeConference contributionScientificpeer-review

1 Citation (Scopus)
38 Downloads (Pure)

Abstract

We show the feasibility of short wave infrared spectroscopy combined with tape stripping as a simple and noninvasive method for the analysis of lipids and the degree of hydration as a function of depth in the stratum corneum. The spectroscopic method utilizes differential detection with three wavelengths 1720, 1750, and 1770 nm, corresponding to the lipid vibrational bands that lay "in between" the prominent water absorption bands. The results are compared with other biophysical devices such as Corneometer and Sebumeter.

Original languageEnglish
Title of host publicationPhotonics in Dermatology and Plastic Surgery 2018
EditorsH. Zeng, B. Choi
PublisherSPIE
Volume10467
ISBN (Electronic)978-151061419-2
DOIs
Publication statusPublished - 2018
EventPhotonics in Dermatology and Plastic Surgery 2018 - San Francisco, United States
Duration: 27 Jan 201828 Jan 2018

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
PublisherSPIE
Volume10467
ISSN (Print)1605-7422

Conference

ConferencePhotonics in Dermatology and Plastic Surgery 2018
CountryUnited States
CitySan Francisco
Period27/01/1828/01/18

Keywords

  • barrier function
  • lipids
  • short-wave infrared spectroscopy
  • stratum corneum
  • Water

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