TY - JOUR
T1 - Electrochemiluminescence reaction pathways in nanofluidic devices
AU - Voci, Silvia
AU - Al-Kutubi, Hanan
AU - Rassaei, Liza
AU - Mathwig, Klaus
AU - Sojic, Neso
PY - 2020
Y1 - 2020
N2 - Nanofluidic electrochemical devices confine the volume of chemical reactions to femtoliters. When employed for light generation by electrochemiluminescence (ECL), nanofluidic confinement yields enhanced intensity and robust luminescence. Here, we investigate different ECL pathways, namely coreactant and annihilation ECL in a single nanochannel and compare light emission profiles. By high-resolution imaging of electrode areas, we show that different reaction schemes produce very different emission profiles in the unique confined geometry of a nanochannel. The confrontation of experimental results with finite element simulation gives further insight into the exact reaction ECL pathways. We find that emission strongly depends on depletion, geometric exclusion, and recycling of reactants in the nanofluidic device.
AB - Nanofluidic electrochemical devices confine the volume of chemical reactions to femtoliters. When employed for light generation by electrochemiluminescence (ECL), nanofluidic confinement yields enhanced intensity and robust luminescence. Here, we investigate different ECL pathways, namely coreactant and annihilation ECL in a single nanochannel and compare light emission profiles. By high-resolution imaging of electrode areas, we show that different reaction schemes produce very different emission profiles in the unique confined geometry of a nanochannel. The confrontation of experimental results with finite element simulation gives further insight into the exact reaction ECL pathways. We find that emission strongly depends on depletion, geometric exclusion, and recycling of reactants in the nanofluidic device.
KW - Electroanalytical methods
KW - Electrochemiluminescence
KW - Fluorescence/luminescence
KW - Nanofluidic device
UR - http://www.scopus.com/inward/record.url?scp=85084150494&partnerID=8YFLogxK
U2 - 10.1007/s00216-020-02630-8
DO - 10.1007/s00216-020-02630-8
M3 - Article
AN - SCOPUS:85084150494
SN - 1618-2642
VL - 412
SP - 4067
EP - 4075
JO - Analytical and Bioanalytical Chemistry
JF - Analytical and Bioanalytical Chemistry
IS - 17
ER -