Evaluation of the Pharmacokinetics and dosimetry of 225Ac Alpha Radionuclide Carriers

Jasper Kouwenberg, Bert Wolterbeek, Antonia Denkova

Research output: Chapter in Book/Conference proceedings/Edited volumeChapterScientific


Introduction: The use of 225Ac for alpha radionuclide therapy is a relatively novel approach, where the dense energy deposition of alpha radiation is used to treat cancer more effectively. 225Ac has, compared to conventional radionuclides, a long half-life of 10 days and a long decay chain, yielding 4 alpha particles, 2 beta particles and several gamma rays. This long decay chain presents new challenges. Daughter radionuclides that separate from the radionuclide carrier during radioactive decay can end up freely circulating …
Original languageEnglish
Title of host publicationFluorescent Nuclear Track Detectors for Alpha Particle Measurement
EditorsJ.J. Kouwenberg
ISBN (Electronic)978-94-6186-911-1
Publication statusPublished - 2018

Publication series

NameFluorescent Nuclear Track Detectors for alpha Particle Measurement


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