Functional Convergence of Autonomic and Sensorimotor Processing in the Lateral Cerebellum

Vincenzo Romano; Aoibhinn L. Reddington; Silvia Cazzanelli; Roberta Mazza; Yang Ma; Christos Strydis; Mario Negrello; Laurens W.J. Bosman; Chris I. De Zeeuw

doi:10.1016/j.celrep.2020.107867

Functional Convergence of Autonomic and Sensorimotor Processing in the Lateral Cerebellum

Vincenzo Romano, Aoibhinn L. Reddington, Silvia Cazzanelli, Roberta Mazza, Yang Ma, Christos Strydis, Mario Negrello^*, Laurens W.J. Bosman^*, Chris I. De Zeeuw

^*Corresponding author for this work

Research output: Contribution to journal › Article › Scientific › peer-review

18 Citations (Scopus)

Abstract

Romano et al. show that cerebellar Purkinje cell activity follows the respiratory rhythm during rest. Triggered by sensory input, Purkinje cells can alter their activity and thereby accelerate the timing of the next inspiration. Concomitantly, they also augment whisker movements, highlighting a coordinating role in aligning autonomic and sensorimotor behaviors.

Original language	English
Article number	107867
Journal	Cell Reports
Volume	32
Issue number	1
DOIs	https://doi.org/10.1016/j.celrep.2020.107867
Publication status	Published - 7 Jul 2020
Externally published	Yes

Keywords

cerebellum
electrophysiology
optogenetics
phase dependent responses
plasticity
Purkinje cells
respiration
sensorimotor behavior
whisker stimulation
whisking

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10.1016/j.celrep.2020.107867

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title = "Functional Convergence of Autonomic and Sensorimotor Processing in the Lateral Cerebellum",

abstract = "Romano et al. show that cerebellar Purkinje cell activity follows the respiratory rhythm during rest. Triggered by sensory input, Purkinje cells can alter their activity and thereby accelerate the timing of the next inspiration. Concomitantly, they also augment whisker movements, highlighting a coordinating role in aligning autonomic and sensorimotor behaviors.",

keywords = "cerebellum, electrophysiology, optogenetics, phase dependent responses, plasticity, Purkinje cells, respiration, sensorimotor behavior, whisker stimulation, whisking",

author = "Vincenzo Romano and Reddington, {Aoibhinn L.} and Silvia Cazzanelli and Roberta Mazza and Yang Ma and Christos Strydis and Mario Negrello and Bosman, {Laurens W.J.} and {De Zeeuw}, {Chris I.}",

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doi = "10.1016/j.celrep.2020.107867",

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AU - Romano, Vincenzo

AU - Reddington, Aoibhinn L.

AU - Cazzanelli, Silvia

AU - Mazza, Roberta

AU - Ma, Yang

AU - Strydis, Christos

AU - Negrello, Mario

AU - Bosman, Laurens W.J.

AU - De Zeeuw, Chris I.

PY - 2020/7/7

Y1 - 2020/7/7

N2 - Romano et al. show that cerebellar Purkinje cell activity follows the respiratory rhythm during rest. Triggered by sensory input, Purkinje cells can alter their activity and thereby accelerate the timing of the next inspiration. Concomitantly, they also augment whisker movements, highlighting a coordinating role in aligning autonomic and sensorimotor behaviors.

AB - Romano et al. show that cerebellar Purkinje cell activity follows the respiratory rhythm during rest. Triggered by sensory input, Purkinje cells can alter their activity and thereby accelerate the timing of the next inspiration. Concomitantly, they also augment whisker movements, highlighting a coordinating role in aligning autonomic and sensorimotor behaviors.

KW - cerebellum

KW - electrophysiology

KW - optogenetics

KW - phase dependent responses

KW - plasticity

KW - Purkinje cells

KW - respiration

KW - sensorimotor behavior

KW - whisker stimulation

KW - whisking

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SN - 2211-1247

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JO - Cell Reports

JF - Cell Reports

IS - 1

M1 - 107867

ER -

Functional Convergence of Autonomic and Sensorimotor Processing in the Lateral Cerebellum

Abstract

Keywords

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