High-Frame-Rate Volumetric Porcine Renal Vasculature Imaging

Luxi Wei*, Geraldi Wahyulaksana, Enrico Boni, Emile Noothout, Dirk J. Duncker, Piero Tortoli, Antonius F.W. van der Steen, Nico de Jong, Martin Verweij, Hendrik J. Vos, More Authors

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

1 Citation (Scopus)
52 Downloads (Pure)

Abstract

Objective: The aim of this study was to assess the feasibility and imaging options of contrast-enhanced volumetric ultrasound kidney vasculature imaging in a porcine model using a prototype sparse spiral array. Methods: Transcutaneous freehand in vivo imaging of two healthy porcine kidneys was performed according to three protocols with different microbubble concentrations and transmission sequences. Combining high-frame-rate transmission sequences with our previously described spatial coherence beamformer, we determined the ability to produce detailed volumetric images of the vasculature. We also determined power, color and spectral Doppler, as well as super-resolved microvasculature in a volume. The results were compared against a clinical 2-D ultrasound machine. Results: Three-dimensional visualization of the kidney vasculature structure and blood flow was possible with our method. Good structural agreement was found between the visualized vasculature structure and the 2-D reference. Microvasculature patterns in the kidney cortex were visible with super-resolution processing. Blood flow velocity estimations were within a physiological range and pattern, also in agreement with the 2-D reference results. Conclusion: Volumetric imaging of the kidney vasculature was possible using a prototype sparse spiral array. Reliable structural and temporal information could be extracted from these imaging results.

Original languageEnglish
Pages (from-to)2476-2482
JournalUltrasound in Medicine and Biology
Volume49
Issue number12
DOIs
Publication statusPublished - 2023

Keywords

  • 3-D ultrasound
  • Contrast-enhanced
  • High frame rate
  • In vivo
  • Kidney
  • Vasculature
  • Volumetric

Fingerprint

Dive into the research topics of 'High-Frame-Rate Volumetric Porcine Renal Vasculature Imaging'. Together they form a unique fingerprint.

Cite this