Insertional mutagenisis combined with acquiered somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

S.J. Howe, M.R. Mansour, K. Schwarzwaelder, C. Bartholomae, M. Hubank, H. Kempski, MH Brugman, K Pike-Overzet, S.J. Chatters, D de Ridder, K.C. Gilmour, S Adams, SI Thornhill, KL Parsley, FJT Staal, RE Gale, DC Linch, J Bayford, L Brown, M QuayeC Kinnon, P Ancliff, DK Webb, M Schmidt, C von Kalle, H.B. Gaspar, A.J. Trasher

Research output: Contribution to journalArticleScientificpeer-review

803 Citations (Scopus)
Original languageUndefined/Unknown
Pages (from-to)3143-3150
Number of pages8
JournalJournal of Clinical Investigation
Volume118
Issue number9
Publication statusPublished - 2008

Keywords

  • academic journal papers
  • CWTS JFIS >= 2.00

Cite this

Howe, S. J., Mansour, M. R., Schwarzwaelder, K., Bartholomae, C., Hubank, M., Kempski, H., Brugman, MH., Pike-Overzet, K., Chatters, S. J., de Ridder, D., Gilmour, K. C., Adams, S., Thornhill, SI., Parsley, KL., Staal, FJT., Gale, RE., Linch, DC., Bayford, J., Brown, L., ... Trasher, A. J. (2008). Insertional mutagenisis combined with acquiered somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients. Journal of Clinical Investigation, 118(9), 3143-3150.