Insertional mutagenisis combined with acquiered somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

S.J. Howe, M.R. Mansour, K. Schwarzwaelder, C. Bartholomae, M. Hubank, H. Kempski, MH Brugman, K Pike-Overzet, S.J. Chatters, D de Ridder, K.C. Gilmour, S Adams, SI Thornhill, KL Parsley, FJT Staal, RE Gale, DC Linch, J Bayford, L Brown, M QuayeC Kinnon, P Ancliff, DK Webb, M Schmidt, C von Kalle, H.B. Gaspar, A.J. Trasher

Research output: Contribution to journalArticleScientificpeer-review

997 Citations (Scopus)
Original languageUndefined/Unknown
Pages (from-to)3143-3150
Number of pages8
JournalJournal of Clinical Investigation
Issue number9
Publication statusPublished - 2008


  • academic journal papers
  • CWTS JFIS >= 2.00

Cite this