Abstract
Functional ultrasound (fUS) is an exciting new neuroimaging technique that is able to record brain activity similar to functional magnetic resonance imaging, yet with higher spatiotemporal resolution and at lower cost. We consider the problem of jointly estimating the underlying neural sources and the hemodynamic response function (HRF) from fUS recordings. We propose to model the measured voxel time-series as a convolutive mixture of multiple source signals and solve the blind deconvolution problem via block-term decomposition. This allows us to estimate both the source time courses and a different HRF for each voxel and source combination, which accounts for the variability of HRF across different brain regions and events respectively. The proposed approach is proven to be robust against noise via simulations and further validated on real fUS data by performing a visual experiment on a mouse. The obtained results show that the proposed method is able to recover the timings of the visual paradigm.
Original language | English |
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Title of host publication | 2020 54th Asilomar Conference on Signals, Systems, and Computers |
Publisher | IEEE |
Pages | 246-250 |
Number of pages | 5 |
ISBN (Electronic) | 978-0-7381-3126-9 |
DOIs | |
Publication status | Published - 2020 |
Event | 54th Asilomar Conference on Signals, Systems, and Computers - Virtual/online event at Pacific Grove, United States Duration: 1 Nov 2020 → 4 Nov 2020 Conference number: 54 https://www.asilomarsscconf.org/PastConferences.html |
Conference
Conference | 54th Asilomar Conference on Signals, Systems, and Computers |
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Abbreviated title | ACSSC 2020 |
Country/Territory | United States |
City | Virtual/online event at Pacific Grove |
Period | 1/11/20 → 4/11/20 |
Internet address |
Bibliographical note
Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-careOtherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.