Large Conductance Variations in a Mechanosensitive Single-Molecule Junction

Davide Stefani, Kevin J. Weiland, Maxim Skripnik, Chunwei Hsu, Mickael L. Perrin, Marcel Mayor*, Fabian Pauly, Herre S.J. Van Der Zant

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

46 Citations (Scopus)
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An appealing feature of molecular electronics is the possibility of inducing changes in the orbital structure through external stimuli. This can provide functionality on the single-molecule level that can be employed for sensing or switching purposes if the associated conductance changes are sizable upon application of the stimuli. Here, we show that the room-temperature conductance of a spring-like molecule can be mechanically controlled up to an order of magnitude by compressing or elongating it. Quantum-chemistry calculations indicate that the large conductance variations are the result of destructive quantum interference effects between the frontier orbitals that can be lifted by applying either compressive or tensile strain to the molecule. When periodically modulating the electrode separation, a conductance modulation at double the driving frequency is observed, providing a direct proof for the presence of quantum interference. Furthermore, oscillations in the conductance occur when the stress built up in the molecule is high enough to allow the anchoring groups to move along the surface in a stick-slip-like fashion. The mechanical control of quantum interference effects results in the largest-gauge factor reported for single-molecule devices up to now, which may open the door for applications in, e.g., a nanoscale mechanosensitive sensing device that is functional at room temperature.

Original languageEnglish
Pages (from-to)5981-5988
JournalNano Letters
Issue number9
Publication statusPublished - 2018


  • density functional theory
  • mechanically controlled break-junctions
  • molecular electronics
  • nanoscale transport
  • Quantum interference
  • single-molecule


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