Measurement of biofilm growth and local hydrodynamics using optical coherence tomography

Nicolás Weiss, Khalid El Tayeb El Obied, Jeroen Kalkman, Rob GH Lammertink, Ton G van Leeuwen

    Research output: Contribution to journalArticleScientificpeer-review

    11 Citations (Scopus)

    Abstract

    We report on localized and simultaneous measurement of biofilm growth and local hydrodynamics in a microfluidic channel using optical coherence tomography. We measure independently with high spatio-temporal resolution the longitudinal flow velocity component parallel to the imaging beam and the transverse flow velocity component perpendicular to the imaging beam. Based on the measured velocities we calculate the shear-rates in the flow channel. We show the relation between the measured biofilm structure and flow velocities as biofilm growth progresses over the course of 48 hours.
    Original languageEnglish
    Pages (from-to)3508-3518
    Number of pages11
    JournalBiomedical Optics Express
    Volume7
    Issue number9
    DOIs
    Publication statusPublished - 2016

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