Measurement of biofilm growth and local hydrodynamics using optical coherence tomography

Nicolás Weiss; Khalid El Tayeb El Obied; Jeroen Kalkman; Rob GH Lammertink; Ton G van Leeuwen

doi:10.1364/BOE.7.003508

Measurement of biofilm growth and local hydrodynamics using optical coherence tomography

Nicolás Weiss, Khalid El Tayeb El Obied, Jeroen Kalkman, Rob GH Lammertink, Ton G van Leeuwen

Research output: Contribution to journal › Article › Scientific › peer-review

15 Citations (Scopus)

Abstract

We report on localized and simultaneous measurement of biofilm growth and local hydrodynamics in a microfluidic channel using optical coherence tomography. We measure independently with high spatio-temporal resolution the longitudinal flow velocity component parallel to the imaging beam and the transverse flow velocity component perpendicular to the imaging beam. Based on the measured velocities we calculate the shear-rates in the flow channel. We show the relation between the measured biofilm structure and flow velocities as biofilm growth progresses over the course of 48 hours.

Original language	English
Pages (from-to)	3508-3518
Number of pages	11
Journal	Biomedical Optics Express
Volume	7
Issue number	9
DOIs	https://doi.org/10.1364/BOE.7.003508
Publication status	Published - 2016

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title = "Measurement of biofilm growth and local hydrodynamics using optical coherence tomography",

abstract = "We report on localized and simultaneous measurement of biofilm growth and local hydrodynamics in a microfluidic channel using optical coherence tomography. We measure independently with high spatio-temporal resolution the longitudinal flow velocity component parallel to the imaging beam and the transverse flow velocity component perpendicular to the imaging beam. Based on the measured velocities we calculate the shear-rates in the flow channel. We show the relation between the measured biofilm structure and flow velocities as biofilm growth progresses over the course of 48 hours.",

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AU - Weiss, Nicolás

AU - El Obied, Khalid El Tayeb

AU - Kalkman, Jeroen

AU - Lammertink, Rob GH

AU - van Leeuwen, Ton G

PY - 2016

Y1 - 2016

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AB - We report on localized and simultaneous measurement of biofilm growth and local hydrodynamics in a microfluidic channel using optical coherence tomography. We measure independently with high spatio-temporal resolution the longitudinal flow velocity component parallel to the imaging beam and the transverse flow velocity component perpendicular to the imaging beam. Based on the measured velocities we calculate the shear-rates in the flow channel. We show the relation between the measured biofilm structure and flow velocities as biofilm growth progresses over the course of 48 hours.

U2 - 10.1364/BOE.7.003508

DO - 10.1364/BOE.7.003508

M3 - Article

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VL - 7

SP - 3508

EP - 3518

JO - Biomedical Optics Express

JF - Biomedical Optics Express

IS - 9

ER -

Measurement of biofilm growth and local hydrodynamics using optical coherence tomography

Abstract

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