Megahertz intravascular Doppler optical coherence tomography enables simultaneous morphological and flow pattern imaging

Tianshi Wang, Tom Pfeiffer, Joost Daemen, Frits Mastik, Wolfgang Wieser, A. F.W. Van Der Steen, Robert Huber, Gijs Van Soest

    Research output: Contribution to journalConference articleScientificpeer-review

    Abstract

    We demonstrate megahertz intravascular Doppler Optical Coherence Tomography (OCT). The OCT system relies on a 1.1 mm diameter motorized catheter and a 1.5 MHz Fourier Domain Mode Locked (FDML) laser. By resolving the phase shift between adjoint A-lines, the flow pattern image can be reconstructed. Imaging experiments were carried out in swine coronary artery in vitro at a speed of 600 frames/s. The MHz sweep rate not only allows us to investigate flow velocity of up to 37.5 cm/s without phase-unwrapping, but also enables dynamic flow imaging at high frame rate.

    Original languageEnglish
    Article number1085503
    Number of pages6
    JournalProgress in Biomedical Optics and Imaging - Proceedings of SPIE
    Volume10855
    DOIs
    Publication statusPublished - 2019
    EventDiagnostic and Therapeutic Applications of Light in Cardiology 2019 - San Francisco, United States
    Duration: 2 Feb 20193 Feb 2019

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