Abstract
A Cu/PMA-MIL-101(Cr) metal-organic-framework-coated microreactor has been applied in the 1,3-dipolar cycloaddition of benzyl azide and phenylactetylene (click chemistry). The Cu/PMA-MIL-101(Cr) catalyst was incorporated by using a washcoating method. The use of tetraethylorthosilicate (TEOS) and a copolymer pluronic F127 as binders resulted in a stable and uniform coating of 6 μm. The application of the Cu/PMA-MIL-101(Cr) capillary microreactor in the click-chemistry reaction resulted in a similar intrinsic activity as in the batch reactor, and a continuous production for more than 150 h time-on-stream could be achieved. The presence of water in the reagent feed led to reversible catalyst deactivation and was necessary to be removed to obtain a stable catalyst operation.
Original language | English |
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Pages (from-to) | 1692-1698 |
Number of pages | 7 |
Journal | ChemCatChem |
Volume | 8 |
Issue number | 9 |
DOIs | |
Publication status | Published - 9 May 2016 |
Keywords
- click chemistry
- copper
- mesoporous materials
- metal-organic frameworks
- microreactors