Mixed-Signal IC With Pulse Width ModulationWireless Telemetry for Implantable CardiacPacemakers in 0.18-μm CMOS

Yasser Rezaeiyan, Milad Zamani, Omid Shoaei, Wouter A. Serdijn

Research output: Contribution to journalArticleScientificpeer-review

7 Citations (Scopus)
28 Downloads (Pure)


A low-power mixed-signal IC for implantable pacemakers is presented. The proposed system features three independent intracardiac signal readout channels with pulse-width-modulated outputs. Also, the proposed system is capable of measuring the amplitude and phase of the bioimpedance with pulse-width-modulated outputs for use in rate adaptive pacemakers. Moreover, a stimulation system is embedded, offering 16 different amplitudes from 1 to 7.8&#x00A0;V. A backscattering transmitter transfers the output signals outside the body with very little power consumption. The proposed low-power mixed-signal IC is fabricated in a 0.18-&#x03BC;m HV CMOS process and occupies 2.38 mm2. The biopotential channels extract the heart signals with 9.2 effective number of bits and the bioimpedance channels measure the amplitude and phase of the heart impedance with 1.35 &#x03A9;<formula><tex>$_{rms}$</tex></formula> accuracy. The complete IC consumes only 4.2&#x00A0;&#x03BC;A from a 1-V power supply.

Original languageEnglish
Pages (from-to)589-600
Number of pages12
JournalIEEE Transactions on Biomedical Circuits and Systems
Issue number3
Publication statusPublished - 2018

Bibliographical note

Accepted Author Manuscript


  • active implantable medical device
  • ASIC
  • bio-impedance
  • bio-potential amplifier
  • cardiac pacemaker
  • Frequency shift keying
  • Heart
  • High-voltage techniques
  • intra-cardiac signal
  • low power
  • Pacemakers
  • Power demand
  • Pulse width modulation
  • Wireless communication
  • wireless communication


Dive into the research topics of 'Mixed-Signal IC With Pulse Width ModulationWireless Telemetry for Implantable CardiacPacemakers in 0.18-<i>μ</i>m CMOS'. Together they form a unique fingerprint.

Cite this