Motif-based analysis of effective connectivity in brain networks

J. Meier, M. Märtens, A. Hillebrand, P. Tewarie, P. Van Mieghem

Research output: Chapter in Book/Conference proceedings/Edited volumeConference contributionScientificpeer-review

1 Citation (Scopus)

Abstract

Network science has widely studied the properties of brain networks. Recent work has observed a global back-to-front pattern of information flow for higher frequency bands in magnetoencephalography data. However, the effective connectivity at a local level remains yet to be analyzed. On a local level, the building blocks of all networks are motifs. In this study, we exploit the measure of dPTE to analyze motifs of the estimated effective connectivity networks. We find that some 3- and 4-motifs, the bidirectional two-hop path and its extended 4-node versions, are significantly overexpressed in the analyzed networks in comparison with random networks. With a recently developed motif-based clustering algorithm we separate the effective connectivity network in two main clusters which reveal its higher-order organization with a strong information flow between posterior hubs and anterior regions.

Original languageEnglish
Title of host publicationComplex Networks and their Applications V
Subtitle of host publicationProceedings of the 5th International Workshop on Complex Networks and their Applications (COMPLEX NETWORKS 2016)
EditorsH. Cherifi, S. Gaito, W. Quattrociocchi, A. Sala
Place of PublicationCham
PublisherSpringer
Pages685-696
Number of pages12
ISBN (Electronic)978-3-319-50901-3
DOIs
Publication statusPublished - 2017
Event5th International Workshop on Complex Networks and their Applications: 5th International Workshop on Complex Networks and their Applications - Milan, Italy
Duration: 30 Nov 20162 Dec 2016
Conference number: 5
http://complexnetworks.org/index2016.html
http://complexnetworks.org/index2016.html

Publication series

NameStudies in Computational Intelligence
Volume693
ISSN (Print)1860-949X

Conference

Conference5th International Workshop on Complex Networks and their Applications
CountryItaly
CityMilan
Period30/11/162/12/16
Internet address

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