Muscle coordination retraining inspired by musculoskeletal simulations reduces knee contact force

Scott D. Uhlrich*, Rachel W. Jackson, Ajay Seth, Julie A. Kolesar, Scott L. Delp

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

14 Citations (Scopus)
25 Downloads (Pure)

Abstract

Humans typically coordinate their muscles to meet movement objectives like minimizing energy expenditure. In the presence of pathology, new objectives gain importance, like reducing loading in an osteoarthritic joint, but people often do not change their muscle coordination patterns to meet these new objectives. Here we use musculoskeletal simulations to identify simple changes in coordination that can be taught using electromyographic biofeedback, achieving the therapeutic goal of reducing joint loading. Our simulations predicted that changing the relative activation of two redundant ankle plantarflexor muscles-the gastrocnemius and soleus-could reduce knee contact force during walking, but it was unclear whether humans could re-coordinate redundant muscles during a complex task like walking. Our experiments showed that after a single session of walking with biofeedback of summary measures of plantarflexor muscle activation, healthy individuals reduced the ratio of gastrocnemius-to-soleus muscle activation by 25 ± 15% (p = 0.004, paired t test, n = 10). Participants who walked with this "gastrocnemius avoidance" gait pattern reduced late-stance knee contact force by 12 ± 12% (p = 0.029, paired t test, n = 8). Simulation-informed coordination retraining could be a promising treatment for knee osteoarthritis and a powerful tool for optimizing coordination for a variety of rehabilitation and performance applications.

Original languageEnglish
Article number9842
Number of pages13
JournalScientific Reports
Volume12
Issue number1
DOIs
Publication statusPublished - 2022

Fingerprint

Dive into the research topics of 'Muscle coordination retraining inspired by musculoskeletal simulations reduces knee contact force'. Together they form a unique fingerprint.

Cite this