Nanomaterials for bone tissue regeneration: Updates and future perspectives

Michael J Hill, Baowen Qi, Rasoul Bayaniahangar, Vida Araban, Zahra Bakhtiary, Michael R. Doschak, Brian C. Goh, Mohammadreza Shokouhimehr, Hojatollah Vali, John F. Presley, Amir A. Zadpoor, Mitchel B. Harris*, Parisa P.S.S. Abadi, Morteza Mahmoudi

*Corresponding author for this work

Research output: Contribution to journalReview articleScientificpeer-review

18 Citations (Scopus)


Joint replacement and bone reconstructive surgeries are on the rise globally. Current strategies for implants and bone regeneration are associated with poor integration and healing resulting in repeated surgeries. A multidisciplinary approach involving basic biological sciences, tissue engineering, regenerative medicine and clinical research is required to overcome this problem. Considering the nanostructured nature of bone, expertise and resources available through recent advancements in nanobiotechnology enable researchers to design and fabricate devices and drug delivery systems at the nanoscale to be more compatible with the bone tissue environment. The focus of this review is to present the recent progress made in the rationale and design of nanomaterials for tissue engineering and drug delivery relevant to bone regeneration.

Original languageEnglish
Pages (from-to)2987-3006
Issue number22
Publication statusPublished - 2019


  • bone
  • drug delivery
  • nanomaterials
  • nanotechnology
  • tissue engineering


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