Natural Deep Eutectic Solvents as Performance Additives for Peroxygenase Catalysis

Yunjian Ma, Yongru Li, Shahid Ali, Peilin Li, Wuyuan Zhang, Marine C.R. Rauch, Sébastien J.P. Willot, Doris Ribitsch, Frank Hollmann, More Authors

Research output: Contribution to journalArticleScientificpeer-review

3 Citations (Scopus)
16 Downloads (Pure)


Natural deep eutectic solvents (NADES) are proposed as alternative solvents for peroxygenase-catalysed oxyfunctionalization reactions. Choline chloride-based NADES are of particular interest as they can serve as solvent, enzyme-stabiliser and sacrificial electron donor for the in situ H2O2 generation. This report provides the first proof-of-concept and basic characterisation of this new reaction system. Highly promising turnover numbers for the biocatalysts of up to 200,000 have been achieved.

Original languageEnglish
Number of pages7
Publication statusPublished - 2019


  • Choline oxidase
  • Deep Eutectic Solvents
  • Oxyfunctionalisation reactions
  • Peroxygenases

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