Non-invasive measurement of intraocular pressure by near-infrared spectroscopy

David Weissbrodt; Ralf Müeller; Juergen Backhaus; Jost B. Jonas

doi:10.1016/j.ajo.2005.01.043

Non-invasive measurement of intraocular pressure by near-infrared spectroscopy

David Weissbrodt, Ralf Müeller, Juergen Backhaus, Jost B. Jonas^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Scientific › peer-review

8 Citations (Scopus)

Abstract

PURPOSE: To assess a new non-contact method for non-invasive measurement of intraocular pressure (IOP) using near-infrared spectroscopy. DESIGN: Experimental study. METHODS: Eleven porcine eyes were cannulated into the anterior chamber by a needle connected with a water column. Measuring the near-infrared spectrum in diffuse reflectance out of the anterior chamber by near-infrared spectroscopy, IOP was determined and compared with the height of the water column which was varied between 0 cm and 100 cm. RESULTS: In total, 363 near-infrared spectrometric measurement values were obtained. Correlating the near-infrared spectrometric measurements with the height of the water column showed a relationship with a correlation coefficient of r² = .858 and a steepness of the regression line of .96. CONCLUSIONS: The results of the present pilot study suggest that near-infrared spectrometric tonometry may present a new technology for non-invasive and non-contact IOP measurement.

Original language	English
Pages (from-to)	307-308
Number of pages	2
Journal	American Journal of Ophthalmology
Volume	140
Issue number	2
DOIs	https://doi.org/10.1016/j.ajo.2005.01.043
Publication status	Published - Aug 2005

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10.1016/j.ajo.2005.01.043

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title = "Non-invasive measurement of intraocular pressure by near-infrared spectroscopy",

abstract = "PURPOSE: To assess a new non-contact method for non-invasive measurement of intraocular pressure (IOP) using near-infrared spectroscopy. DESIGN: Experimental study. METHODS: Eleven porcine eyes were cannulated into the anterior chamber by a needle connected with a water column. Measuring the near-infrared spectrum in diffuse reflectance out of the anterior chamber by near-infrared spectroscopy, IOP was determined and compared with the height of the water column which was varied between 0 cm and 100 cm. RESULTS: In total, 363 near-infrared spectrometric measurement values were obtained. Correlating the near-infrared spectrometric measurements with the height of the water column showed a relationship with a correlation coefficient of r2 = .858 and a steepness of the regression line of .96. CONCLUSIONS: The results of the present pilot study suggest that near-infrared spectrometric tonometry may present a new technology for non-invasive and non-contact IOP measurement.",

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T1 - Non-invasive measurement of intraocular pressure by near-infrared spectroscopy

AU - Weissbrodt, David

AU - Müeller, Ralf

AU - Backhaus, Juergen

AU - Jonas, Jost B.

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N2 - PURPOSE: To assess a new non-contact method for non-invasive measurement of intraocular pressure (IOP) using near-infrared spectroscopy. DESIGN: Experimental study. METHODS: Eleven porcine eyes were cannulated into the anterior chamber by a needle connected with a water column. Measuring the near-infrared spectrum in diffuse reflectance out of the anterior chamber by near-infrared spectroscopy, IOP was determined and compared with the height of the water column which was varied between 0 cm and 100 cm. RESULTS: In total, 363 near-infrared spectrometric measurement values were obtained. Correlating the near-infrared spectrometric measurements with the height of the water column showed a relationship with a correlation coefficient of r2 = .858 and a steepness of the regression line of .96. CONCLUSIONS: The results of the present pilot study suggest that near-infrared spectrometric tonometry may present a new technology for non-invasive and non-contact IOP measurement.

AB - PURPOSE: To assess a new non-contact method for non-invasive measurement of intraocular pressure (IOP) using near-infrared spectroscopy. DESIGN: Experimental study. METHODS: Eleven porcine eyes were cannulated into the anterior chamber by a needle connected with a water column. Measuring the near-infrared spectrum in diffuse reflectance out of the anterior chamber by near-infrared spectroscopy, IOP was determined and compared with the height of the water column which was varied between 0 cm and 100 cm. RESULTS: In total, 363 near-infrared spectrometric measurement values were obtained. Correlating the near-infrared spectrometric measurements with the height of the water column showed a relationship with a correlation coefficient of r2 = .858 and a steepness of the regression line of .96. CONCLUSIONS: The results of the present pilot study suggest that near-infrared spectrometric tonometry may present a new technology for non-invasive and non-contact IOP measurement.

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Non-invasive measurement of intraocular pressure by near-infrared spectroscopy

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