Abstract
The recent start-up of several full-scale ‘second generation’ ethanol plants marks a major milestone in the development of Saccharomyces cerevisiae yeast strains for fermentation of lignocellulosic hydrolysates of agricultural residues and energy crops. In contrast to the fermentation of hexose sugar-rich substrates, such as corn syrup or sugar cane bagasse, these hydrolysates contain mixtures of the hexose sugar D-glucose and the pentose sugars D-xylose and L-arabinose. While S. cerevisiae performs excellently in fermenting hexose sugars to ethanol, efficient utilization of pentose sugars required extensive metabolic and evolutionary engineering.
Original language | English |
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Qualification | Doctor of Philosophy |
Awarding Institution |
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Thesis sponsors | |
Award date | 6 Sept 2018 |
Print ISBNs | 978-94-6186-944-9 |
DOIs | |
Publication status | Published - 2018 |
Keywords
- pentose fermentation
- xylose
- arabinose
- Saccharomyces cerevisiae
- Yeast
- Biotechnology
- Lignocellulosic biofuels
- Ethanol