POLAR MAPPER: A computational tool for integrated visualization of protein interaction networks and mRNA expression data

Joana P. Goncalves; Mário Grãos; Andre X. C. N. Valente

doi:10.1098/rsif.2008.0407

POLAR MAPPER: A computational tool for integrated visualization of protein interaction networks and mRNA expression data

Joana P. Goncalves, Mário Grãos, Andre X. C. N. Valente

Research output: Contribution to journal › Article › Scientific › peer-review

10 Citations (Scopus)

Abstract

Polar Mapper is a computational application for exposing the architecture of protein interaction networks. It facilitates the system-level analysis of mRNA expression data in the context of the underlying protein interaction network. Preliminary analysis of a human protein interaction network and comparison of the yeast oxidative stress and heat shock gene expression responses are addressed as case studies.

Original language	English
Pages (from-to)	881-896
Number of pages	16
Journal	Journal of the Royal Society Interface
Volume	6
Issue number	39
DOIs	https://doi.org/10.1098/rsif.2008.0407
Publication status	Published - 6 Oct 2009
Externally published	Yes

Keywords

protein interaction network
functional genomics
systems biology

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10.1098/rsif.2008.0407

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title = "POLAR MAPPER: A computational tool for integrated visualization of protein interaction networks and mRNA expression data",

abstract = "Polar Mapper is a computational application for exposing the architecture of protein interaction networks. It facilitates the system-level analysis of mRNA expression data in the context of the underlying protein interaction network. Preliminary analysis of a human protein interaction network and comparison of the yeast oxidative stress and heat shock gene expression responses are addressed as case studies.",

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year = "2009",

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T2 - A computational tool for integrated visualization of protein interaction networks and mRNA expression data

AU - Goncalves, Joana P.

AU - Grãos, Mário

AU - Valente, Andre X. C. N.

PY - 2009/10/6

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AB - Polar Mapper is a computational application for exposing the architecture of protein interaction networks. It facilitates the system-level analysis of mRNA expression data in the context of the underlying protein interaction network. Preliminary analysis of a human protein interaction network and comparison of the yeast oxidative stress and heat shock gene expression responses are addressed as case studies.

KW - protein interaction network

KW - functional genomics

KW - systems biology

U2 - 10.1098/rsif.2008.0407

DO - 10.1098/rsif.2008.0407

M3 - Article

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SP - 881

EP - 896

JO - Journal of the Royal Society Interface

JF - Journal of the Royal Society Interface

IS - 39

ER -

POLAR MAPPER: A computational tool for integrated visualization of protein interaction networks and mRNA expression data

Abstract

Keywords

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