POLAR MAPPER: A computational tool for integrated visualization of protein interaction networks and mRNA expression data

Joana P. Goncalves, Mário Grãos, Andre X. C. N. Valente

Research output: Contribution to journalArticleScientificpeer-review

10 Citations (Scopus)

Abstract

Polar Mapper is a computational application for exposing the architecture of protein interaction networks. It facilitates the system-level analysis of mRNA expression data in the context of the underlying protein interaction network. Preliminary analysis of a human protein interaction network and comparison of the yeast oxidative stress and heat shock gene expression responses are addressed as case studies.
Original languageEnglish
Pages (from-to)881-896
Number of pages16
JournalJournal of the Royal Society Interface
Volume6
Issue number39
DOIs
Publication statusPublished - 6 Oct 2009
Externally publishedYes

Keywords

  • protein interaction network
  • functional genomics
  • systems biology

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