POLAR MAPPER: A computational tool for integrated visualization of protein interaction networks and mRNA expression data

Joana P. Goncalves; Mário Grãos; Andre X. C. N. Valente

doi:10.1098/rsif.2008.0407

POLAR MAPPER: A computational tool for integrated visualization of protein interaction networks and mRNA expression data

Joana P. Goncalves, Mário Grãos, Andre X. C. N. Valente

Research output: Contribution to journal › Article › Scientific › peer-review

12 Citations (Scopus)

Abstract

Polar Mapper is a computational application for exposing the architecture of protein interaction networks. It facilitates the system-level analysis of mRNA expression data in the context of the underlying protein interaction network. Preliminary analysis of a human protein interaction network and comparison of the yeast oxidative stress and heat shock gene expression responses are addressed as case studies.

Original language	English
Pages (from-to)	881-896
Number of pages	16
Journal	Journal of the Royal Society Interface
Volume	6
Issue number	39
DOIs	https://doi.org/10.1098/rsif.2008.0407
Publication status	Published - 6 Oct 2009
Externally published	Yes

Keywords

protein interaction network
functional genomics
systems biology

Access to Document

10.1098/rsif.2008.0407

Cite this

@article{68de02d6f1874bcb9d590ef546a35363,

title = "POLAR MAPPER: A computational tool for integrated visualization of protein interaction networks and mRNA expression data",

abstract = "Polar Mapper is a computational application for exposing the architecture of protein interaction networks. It facilitates the system-level analysis of mRNA expression data in the context of the underlying protein interaction network. Preliminary analysis of a human protein interaction network and comparison of the yeast oxidative stress and heat shock gene expression responses are addressed as case studies.",

keywords = "protein interaction network, functional genomics, systems biology",

author = "Goncalves, {Joana P.} and M{\'a}rio Gr{\~a}os and Valente, {Andre X. C. N.}",

year = "2009",

month = oct,

day = "6",

doi = "10.1098/rsif.2008.0407",

language = "English",

volume = "6",

pages = "881--896",

journal = "Journal of the Royal Society Interface",

issn = "1742-5689",

publisher = "Royal Society of London",

number = "39",

}

TY - JOUR

T1 - POLAR MAPPER

T2 - A computational tool for integrated visualization of protein interaction networks and mRNA expression data

AU - Goncalves, Joana P.

AU - Grãos, Mário

AU - Valente, Andre X. C. N.

PY - 2009/10/6

Y1 - 2009/10/6

N2 - Polar Mapper is a computational application for exposing the architecture of protein interaction networks. It facilitates the system-level analysis of mRNA expression data in the context of the underlying protein interaction network. Preliminary analysis of a human protein interaction network and comparison of the yeast oxidative stress and heat shock gene expression responses are addressed as case studies.

AB - Polar Mapper is a computational application for exposing the architecture of protein interaction networks. It facilitates the system-level analysis of mRNA expression data in the context of the underlying protein interaction network. Preliminary analysis of a human protein interaction network and comparison of the yeast oxidative stress and heat shock gene expression responses are addressed as case studies.

KW - protein interaction network

KW - functional genomics

KW - systems biology

U2 - 10.1098/rsif.2008.0407

DO - 10.1098/rsif.2008.0407

M3 - Article

SN - 1742-5689

VL - 6

SP - 881

EP - 896

JO - Journal of the Royal Society Interface

JF - Journal of the Royal Society Interface

IS - 39

ER -

POLAR MAPPER: A computational tool for integrated visualization of protein interaction networks and mRNA expression data

Abstract

Keywords

Access to Document

Fingerprint

Cite this