A biocatalytic cascade transforming castor oil into (R,Z)-octadec-9-en-7-ol is presented by combining a lipase catalysed hydrolysis of castor oil into ricinoleic acid followed by a photoenzymatic decarboxylation into (R,Z)-octadec-9-en-7-ol. Conversion of up to 41.7% and overall product concentrations of up to 60 mM, this new bienzymatic and photocatalytic cascade exhibits significant potential for the valorisation of non-edible castor oil. The scope and limitations of the current system are described and discussed.
Ma, Y., Zhang, X., Li, Y., Li, P., Hollmann, F., & Wang, Y. (2020). Production of fatty alcohols from non-edible oils by enzymatic cascade reactions. Sustainable Energy & Fuels, 4(8), 4232-4237. https://doi.org/10.1039/D0SE00848F