Scale-spaces from protein networks: How diffusion profiles reveal functional information in physical interaction topologies

Christos Dimitrakopoulos, Marc Hulsman, Jeroen de Ridder

Research output: Contribution to conferencePosterScientific

Abstract

Summary

Understanding the living cell as a system of interconnected components is one of the key contemporary challenges. This is a complex problem, in which different types of functional interactions play a role, each operating across multiple distinct scales.

How do functional interactions emerge
from the topology of the physical interaction network?

To investigate this we explore scale independent descriptions of the topology of the physical protein-protein and protein-DNA interaction networks in yeast.
Original languageEnglish
Pages1-1
Number of pages1
Publication statusPublished - Mar 2012
EventSystems Biology: Global Regulation of Gene Expression - New York, United States
Duration: 20 Mar 201224 Mar 2012

Conference

ConferenceSystems Biology
Country/TerritoryUnited States
CityNew York
Period20/03/1224/03/12

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