Synthetic Biology to Engineer Bacteriophage Genomes

Ana Rita Costa, Joana Azeredo, Diana Priscila Pires*

*Corresponding author for this work

Research output: Chapter in Book/Conference proceedings/Edited volumeChapterScientific

2   Link opens in a new tab Citations (SciVal)
39 Downloads (Pure)

Abstract

Recent advances in the synthetic biology field have enabled the development of new molecular biology techniques used to build specialized bacteriophages with new functionalities. Bacteriophages have been engineered toward a wide range of applications, including pathogen control and detection, targeted drug delivery, or even assembly of new materials. In this chapter, two strategies that have been successfully used to genetically engineer bacteriophage genomes will be addressed: the bacteriophage recombineering of electroporated DNA (BRED) and the yeast-based phage-engineering platform.

Original languageEnglish
Title of host publicationBacteriophage Therapy
Subtitle of host publicationFrom Lab to Clinical Practice
EditorsJoana Azeredo, Sanna Sillankorva
PublisherHumana Press Inc.
Chapter17
Pages261-277
Number of pages17
Edition2nd
DOIs
Publication statusPublished - 2024

Publication series

NameMethods in Molecular Biology
Volume2734
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Bibliographical note

Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.

Keywords

  • Bacteriophage
  • Bacteriophage engineering
  • BRED
  • YAC

Fingerprint

Dive into the research topics of 'Synthetic Biology to Engineer Bacteriophage Genomes'. Together they form a unique fingerprint.

Cite this