TY - JOUR
T1 - Synthetic life on a chip
AU - Deshpande, Siddharth
AU - Dekker, Cees
N1 - Accepted Author Manuscript
PY - 2019
Y1 - 2019
N2 - In this article, we argue that on-chip microfluidic systems provide an attractive technology when it comes to designing synthetic cells. We emphasize the importance of the surrounding environment for both living systems in nature and for developing artificial self-sustaining entities. On-chip microfluidic devices provide a high degree of control over the production of cell-like synthetic entities as well as over the local microenvironment that these soft-matter-based synthetic cells experience. Rapid progress in microfluidic fabrication technology has led to a variety of production and manipulation tools that establish on-chip environments as a versatile platform and arguably the best route forward for realizing synthetic life.
AB - In this article, we argue that on-chip microfluidic systems provide an attractive technology when it comes to designing synthetic cells. We emphasize the importance of the surrounding environment for both living systems in nature and for developing artificial self-sustaining entities. On-chip microfluidic devices provide a high degree of control over the production of cell-like synthetic entities as well as over the local microenvironment that these soft-matter-based synthetic cells experience. Rapid progress in microfluidic fabrication technology has led to a variety of production and manipulation tools that establish on-chip environments as a versatile platform and arguably the best route forward for realizing synthetic life.
UR - http://www.scopus.com/inward/record.url?scp=85092941395&partnerID=8YFLogxK
U2 - 10.1042/ETLS20190097
DO - 10.1042/ETLS20190097
M3 - Article
AN - SCOPUS:85092941395
SN - 2397-8554
VL - 3
SP - 559
EP - 566
JO - Emerging Topics in Life Sciences
JF - Emerging Topics in Life Sciences
IS - 5
ER -