The greening of solvents: Towards sustainable organic synthesis

Roger A. Sheldon*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

92 Citations (Scopus)


Recent developments in the evolution of more sustainable solvent use in organic synthesis are critically reviewed. Commonly used organic solvents and less common bio-based examples are assessed and ranked on the basis of waste disposal and environmental impact, health and safety parameters. The use of water as a solvent, including the use of aqueous biphasic catalysis, micelle-enabled catalysis and biocatalysis, constitutes a viable, green and sustainable alternative to reactions in organic solvents.

Original languageEnglish
Pages (from-to)13-19
JournalCurrent Opinion in Green and Sustainable Chemistry
Publication statusPublished - 2019


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