Theoretical analysis of coronary blood flow and tissue oxygen pressure-control

Jos A.E. Spaan, Jenny Dankelman

Research output: Chapter in Book/Conference proceedings/Edited volumeChapterScientific

Abstract

Coronary blood flow is tightly coupled to the myocardial oxygen consumption. We have presented a control model based on the assumption that the tissue oxygen pressure is the controlled variable. The coronary blood flow in itself is not a controlled variable but merely the result of a different control system: the tissue oxygen pressure. From our control equation there is no relation between the slope of the autoregulation curve and the gain of the tissue P02 control system. The slope is independent of the level of oxygen consumption.
Original languageEnglish
Title of host publicationInteractive Phenomena in the Cardiac System
EditorsS Sideman, R Beyar
Place of PublicationBoston, MA, USA
PublisherSpringer
Chapter18
Pages189-195
ISBN (Electronic)978-1-4615-2946-0
ISBN (Print)978-1-4613-6280-7
Publication statusPublished - 1993

Publication series

NameAdvances in Experimental Medicine and Biology book series
PublisherSpringer
Volume346

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  • Cite this

    Spaan, J. A. E., & Dankelman, J. (1993). Theoretical analysis of coronary blood flow and tissue oxygen pressure-control. In S. Sideman, & R. Beyar (Eds.), Interactive Phenomena in the Cardiac System (pp. 189-195). (Advances in Experimental Medicine and Biology book series; Vol. 346). Springer. https://link.springer.com/chapter/10.1007/978-1-4615-2946-0_18