Unraveling proteins at the single molecule level using nanopores

Laura Restrepo Perez

Research output: ThesisDissertation (TU Delft)

118 Downloads (Pure)

Abstract

The function and phenotype of a cell is determined by a complex network of interactions between DNA, RNA, proteins and metabolites. Therefore, a comprehensive approach that integrates genomics, transcriptomics, proteomics, and metabolomics is necessary to achieve full understanding of biological processes and disease. Recent technological developments have mostly focused on the study of genomes. DNA sequencing has become fast, cheap, and ubiquitous. The study of other -omes, especially the proteome, remains expensive and time-consuming...
Original languageEnglish
Awarding Institution
  • Delft University of Technology
Supervisors/Advisors
  • Dekker, C., Supervisor
  • Joo, C., Supervisor
Award date10 May 2019
Print ISBNs978.90.8593.395.3
DOIs
Publication statusPublished - 2019

Keywords

  • Single-molecule protein
  • sequencing
  • protein fingerprinting
  • proteins
  • nanopores
  • post-translational modifications

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