Abstract
Peroxyzymes simply use H2O2 as a cosubstrate to oxidize a broad range of inert C-H bonds. The lability of many peroxyzymes against H2O2 can be addressed by a controlled supply of H2O2, ideally in situ. Here, we report a simple, robust, and water-soluble anthraquinone sulfonate (SAS) as a promising organophotocatalyst to drive both haloperoxidase-catalyzed halogenation and peroxygenase-catalyzed oxyfunctionalization reactions. Simple alcohols, methanol in particular, can be used both as a cosolvent and an electron donor for H2O2 generation. Very promising turnover numbers for the biocatalysts of up to 318 »000 have been achieved.
Original language | English |
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Pages (from-to) | 8277-8284 |
Journal | ACS Catalysis |
Volume | 10 |
Issue number | 15 |
DOIs | |
Publication status | Published - 2020 |
Keywords
- HOgeneration
- halogenation
- hydroxylation
- peroxyzymes
- photobiocatalysis