Acoustic biosensors

Alper Sisman*, Paddy French, Ayse Ogan, Erdal Korkmaz, Abbas A. Husseini, Ali M. Yazdani, Johan Meyer

*Corresponding author for this work

Research output: Chapter in Book/Conference proceedings/Edited volumeChapterScientificpeer-review


Acoustics has high variety of applications ranging from structural-health monitoring, sonar, and biological applications to sensors. The acoustic domain employs pressure waves for detection and provides better performance for sensing applications that require interactions with mechanical signals. High-performance sensing is possible by using acoustic biosensors in biological applications since most of the biological signals are in mechanical domain, in which the sensing mechanism directly interacts with them. In this chapter, the physics for different acoustic modes are introduced and their specific applications are mentioned, as well as sensing principles and operating mechanisms are presented. Also, the structural perspectives for acoustic biosensors are given and the fabrication techniques and materials are described. In this chapter, the biochemical principles behind the sensing are introduced and the layers and surfaces interacting with biomolecules are discussed. Some of the commercially available acoustic biosensors are presented and a short discussion of future perspectives is given.

Original languageEnglish
Title of host publicationAcoustic Technologies in Biology and Medicine
EditorsAdem Ozcelik, Ryan Becker, Tony Jun Huang
Number of pages37
ISBN (Electronic)9783527841325
ISBN (Print)9783527350629
Publication statusPublished - 2023


  • Biomarker detection
  • Biomaterial level quantification
  • Biosensors
  • Bulk acoustic waves
  • Surface acoustic waves
  • Surface functionalization
  • Wave modes


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