Compartmentalizing Supramolecular Hydrogels Using Aqueous Multi‐phase Systems

Serhii Mytnyk; Alexandre G.L. Olive; Frank Versluis; Jos M. Poolman; Eduardo Mendes; Rienk Eelkema; Jan H. van Esch

doi:10.1002/anie.201706272

Compartmentalizing Supramolecular Hydrogels Using Aqueous Multi‐phase Systems

Serhii Mytnyk, Alexandre G.L. Olive, Frank Versluis, Jos M. Poolman, Eduardo Mendes, Rienk Eelkema, Jan H. van Esch^*

^*Corresponding author for this work

ChemE/Advanced Soft Matter

Research output: Contribution to journal › Article › Scientific › peer-review

31 Citations (Scopus)

Abstract

A generic method is used for compartmentalization of supramolecular hydrogels by using water-in-water emulsions based on aqueous multi-phase systems (AMPS). By forming the low-molecular-weight hydrogel throughout all phases of all-aqueous emulsions, distinct, micro-compartmentalized materials were created. This structuring approach offers control over the composition of each type of the compartments by directing the partitioning of objects to be encapsulated. Moreover, this method allows for barrier-less, dynamic exchange of even large hydrophilic solutes (MW≈60kDa) between separate aqueous compartments. These features are expected to find use in the fields of, for instance, micro-structured catalysts, templating, and tissue engineering.

Original language	English
Pages (from-to)	14923-14927
Number of pages	5
Journal	Angewandte Chemie (International Edition)
Volume	56
Issue number	47
DOIs	https://doi.org/10.1002/anie.201706272
Publication status	Published - 2017

Keywords

Aqueous systems
Colloids
Compartmentalization
Gels
Multi-phase systems

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10.1002/anie.201706272

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title = "Compartmentalizing Supramolecular Hydrogels Using Aqueous Multi‐phase Systems",

abstract = "A generic method is used for compartmentalization of supramolecular hydrogels by using water-in-water emulsions based on aqueous multi-phase systems (AMPS). By forming the low-molecular-weight hydrogel throughout all phases of all-aqueous emulsions, distinct, micro-compartmentalized materials were created. This structuring approach offers control over the composition of each type of the compartments by directing the partitioning of objects to be encapsulated. Moreover, this method allows for barrier-less, dynamic exchange of even large hydrophilic solutes (MW≈60kDa) between separate aqueous compartments. These features are expected to find use in the fields of, for instance, micro-structured catalysts, templating, and tissue engineering.",

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AU - Mytnyk, Serhii

AU - Olive, Alexandre G.L.

AU - Versluis, Frank

AU - Poolman, Jos M.

AU - Mendes, Eduardo

AU - Eelkema, Rienk

AU - van Esch, Jan H.

PY - 2017

Y1 - 2017

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AB - A generic method is used for compartmentalization of supramolecular hydrogels by using water-in-water emulsions based on aqueous multi-phase systems (AMPS). By forming the low-molecular-weight hydrogel throughout all phases of all-aqueous emulsions, distinct, micro-compartmentalized materials were created. This structuring approach offers control over the composition of each type of the compartments by directing the partitioning of objects to be encapsulated. Moreover, this method allows for barrier-less, dynamic exchange of even large hydrophilic solutes (MW≈60kDa) between separate aqueous compartments. These features are expected to find use in the fields of, for instance, micro-structured catalysts, templating, and tissue engineering.

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KW - Gels

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Compartmentalizing Supramolecular Hydrogels Using Aqueous Multi‐phase Systems

Abstract

Keywords

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Microfabrication and microstructuring of hydrogel materials

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